CCL-121 HT-1080 人纖維肉瘤
ATCC® Number: CCL-121?
Designations: HT-1080
Biosafety Level: 1
Shipped: frozen
Medium & Serum: See Propagation
Growth Properties: adherent
Organism: Homo sapiens (human)
Morphology: epithelial
Source: Tissue: connective tissue
Disease: fibrosarcoma
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Isolation: Isolation date: July, 1972
Applications: transfection host (Nucleofection technology from Lonza
Roche FuGENE® Transfection Reagents)
Virus Susceptibility: Human poliovirus 1
RD-114 Feline
Feline leukemia virus
Vesicular stomatitis virus
Tumorigenic: Yes
Reverse Transcript: negative
Oncogene: ras +
DNA Profile (STR): Amelogenin: X,Y
CSF1PO: 12
D13S317: 12,14
D16S539: 9,12
D5S818: 11,13
D7S820: 9,10
THO1: 6
TPOX: 8
vWA: 14,19
Cytogenetic Analysis: modal number = 46; range = 44 to 48.
Pseudodiploidy was frequently noted. About 40% of the cells had rearranged karyotypes with an extra E-group chromosome and a group C chromosome, probably chromosome 11, was missing.
Isoenzymes: G6PD, B
Age: 35 years
Gender: male